miRNAs in human cancer

miRNAs in human cancer.

Mature microRNAs (miRNAs) are single-stranded RNA molecules of 20-23 nucleotide (nt) length that control gene expression in many cellular processes. These molecules typically reduce the stability of mRNAs, including those of genes that mediate processes in tumorigenesis, such as inflammation, cell cycle regulation, stress response, differentiation, apoptosis and invasion. miRNA targeting is mos...

Diagnostic Utility of miRNAs in Cancer

Cancer is the one of most prevalent and leading causes of death in the world. Current ad­vancements in technology improve the understanding of the pathogenesis and pathology of cancers. But, due to enlarging mortality rates, poor prognosis, and lacunae in clinical early predictive biomarkers provide an important momentum to investigate novel early diagnos­tic/prognostic markers and spec...

Diagnostic Utility of miRNAs in Cancer

Cancer is the one of most prevalent and leading causes of death in the world. Current ad­vancements in technology improve the understanding of the pathogenesis and pathology of cancers. But, due to enlarging mortality rates, poor prognosis, and lacunae in clinical early predictive biomarkers provide an important momentum to investigate novel early diagnos­tic/prognostic markers and spec...

miRNAs in Pancreatic Cancer

miRNAs and cancer

MicroRNAs (miRNAs) are small 21-25 nucleotide RNA molecules that comprise an evolutionarily conserved class of ribo-regulators which modulate gene expression via the RNA interference pathway. Initially considered a peculiarity of nematodes it is now known that these small non protein coding RNAs also occur in a wide variety of other organisms like plants, arthropods and vertebrates such as amph...